Brand Name or Equal Nikon multi-camera X1-based spinning disk confocal microscope system

SOURCES SOUGHT NOTICE: Brand Name or Equal Nikon multi-camera X1-based spinning disk confocal microscope system.Notice Number:75N91019Q00051Issued By:National Cancer Institute (NCI),Office of Acquisitions (OA)http://www.nci.nih.gov or http://rcb.cancer.gov/rcb-internet/Key Dates:Capability Statement Due Date: April 24, 2019 by 12:00PM Eastern Standard Time.This Small Business Sources Sought Notice (SBSS) is for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the National Cancer Institute (NCI).The purpose of this Sources Sought Notice is to identify qualified Small Business concerns including 8(a), HUBZone or Service-Disabled Veteran-owned businesses that are interested in and capable of performing the work described herein. The NCI does not intend to award a

contract on the basis of responses received nor otherwise pay for the preparation of any information submitted. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This requirement is assigned North American Industry Classification System (NAICS) code 334516 with a size standard of 1000 employees.As a result of this Sources Sought Notice, the NCI may issue a Request for Quotation (RFQ). THERE IS NO SOLICITATION AVAILABLE AT THIS TIME. However, should such a requirement materialize, no basis for claims against NCI shall arise as a result of a response to this Sources Sought Notice or the NCI's use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement.The Laboratory of Cellular and Molecular Biology has several projects that require a fast and sensitive microscope for performing live cell imaging. High-speed image capture often requires the use of a spinning-disk confocal system equipped with multiple detectors. Specifically, it needs a light microscope confocal system with the capability to image live cells in 3 channels simultaneously with high resolution (diffraction limited resolution of 250 nm resolution for fluorophores emitting at 525 nm in fixed cells) for experiments on activation of T cells (best done with 3 sCMOS cameras), to visualize single molecules in live cells at least two simultaneous channels for experiments on localized mRNA (best done with a back-thinned sCMOS camera) equipped with a chip splitter) and to image at least two simultaneous channels at high resolution in live animals for experiments on membrane remodeling (either camera system).The National Cancer Institute (NCI), Center for Cancer Research (CCR), Laboratory of Cellular and Molecular Biology (LCMB) plans to procure Nikon multi-camera X1-based spinning disk confocal microscope system.The Contractor shall meet the following product features/characteristics for this requirement:1. Eclipse Ti2-E inverted microscope with PFS 4, motorized stage and Z piezo including all needed optical components, cords and hardware.2. Epifluorescence components kit including SOLA SE II 365 Light Engine, filters and dichroic mirrors.3. CFI60 Plan Apochromat Lambda 10x Objective Lens, N.A. 0.45, W.D. 4.0mm, F.O.V.25mm, DIC, Spring Loaded.4. CFI60 Plan Apochromat Lambda 20x Objective Lens, N.A. 0.75, W.D. 1.0mm, F.O.V.25mm, DIC, Spring Loaded.5. CFI60 Plan Apochromat Lambda 40x Oil Immersion Objective Lens, N.A. 1.3, W.D. 0.2mm, F.O.V. 25mm, DIC, Spring Loaded.6. CFI60 Plan Apochromat Lambda S 60x Oil Immersion Objective Lens, N.A. 1.4, W.D. 0.12mm, F.O.V. 22mm, DIC, Spring Loaded.7. CFI60 Plan Apochromat TIRF 100x Oil Immersion Objective Lens, N.A. 1.49, W.D. 0.12mm, F.O.V. 22mm, DIC, Spring Loaded.8. CFI60 Plan Apochromat Lambda S 100x Silicone Immersion Objective Lens,N.A. 1.35,W.D. 0.3mm, F.O.V. 22mm, DIC, Correction Collar 0.15-0.19mm.9. DIC optical components, cubes, turrets and condenser elements for all objectives.10. CSU-X1 with 7-line laser combiner along with needed dichroic mirrors, filters, adapters and controllers.11. LUNV Laser Unit with alignment-free beam combiner and AOTF modulation (laser lines 405nm(20mw)/ 445nm(20mw)/ 488nm(20mw)/515nm(20mw)/ 561nm(20mw)/ 594nm(20mw)/ 640nm(40mw) with 2 single mode optical fiber outputs, along with all required fiber optic cables, controllers, filters and connectors.12. Three (3) ORCA-Flash4.0 V3 sCMOS Camera with 82% High Quantum Efficiency and multi-camera emission splitter, with all associated optical elements including cables, mounts, adapters, filters, dichoroic mirrors and holders.13. Photometrics Prime 95B Back-illuminated sCMOS Camera with W-View Gemini Image Splitter and all associated components, filters and dichroic mirrors.14. Advanced Biosystems Workstation - HP Z840 featuring dual Intel Xeon 2.6GHz processors (8 cores total), 128GB DDR4 2400 Mhz RAM, GTX 1080 8GBGDDR5X GPU,512GB Turbo SSD for OS, 4TB (2GBx2 Raid 0) data storage, 2xGb LAN ethernet, 8x USB3 and 2x USB2 ports, keyboard and optical mouse. Windows 10 64-bit Professional. Includes 3 years warranty for parts, labor, and service. All connectors for computer and devices.15. 30" LED Backlit IPS monitor with height, swivel, and tilt adjustment. Connects to PC by VGA, Display Port, DVI-D, HDMI. 178° viewing angle, 2560x1600. Includes 3 years parts, labor, and on-site service warranty.16. NIS-Elements,6D imaging acquisition module, JOBS acquisition module, hardware modules, device control modules, Triple/quad camera module, Advanced analysis package for large number of objects, cables and connectors.17. Device Control for Externally Triggering a Device Through a Camera and Device control for of Sutter DG4/5, AOTF, Agilent, Lumencor SpectraX, Spinning Disk and others.18. DMD module with multi-line LED source.19. Galvo-based FRAP/photoactivation device and 405 nm laser, mounts and connectors.20. Tokai Hit STXG Incubation system for wellplates, slides and dishes with magneticsample holder inserts, temperature controller and built-in digital gas mixer.21. Installation and training of users.22. A minimum of 12-month warranty must be provided.How to Submit a Response:1. Page Limitations:Interested qualified small business organizations should submit a tailored capability statement for this requirement not to exceed 10 single sided pages including all attachments, resumes, charts, etc. (single spaced, 12-point font minimum) that clearly details the ability to perform the requirements of the notice described above. All proprietary information should be marked as such. Responses should include a minimum of a one page resume of the individuals meeting the requirements, and up to two pages demonstrating experience over the past two years meeting the requirements of this notice. Statements should also include an indication of current small business status; this indication should be clearly marked on the first page of your capability statement (preferable placed under the eligible small business concern's name and address). Responses will be reviewed only by NIH personnel and will be held in a confidential manner. Organizations shall demonstrate 1.) Technical Approach 2.) Personnel Requirements and Organizational Experience.2. Due Date:Capability statements are due no later than April 24, 2019 by 12:00PM Eastern Standard Time.3. Delivery Point:All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the unique specifications described herein. All questions must be in writing and emailed to David.Romley@nih.gov. A determination by the Government not to compete this requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA) through sam.gov. No collect calls will be accepted. Please reference number 75N91019Q00051 on all correspondence.Disclaimer and Important Notes:This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a RFQ may be published in Fed Biz Opps. However, responses to this notice will not be considered adequate responses to a solicitation(s).Point of Contact:Inquiries concerning this Notice may be direct to:David Romley at David.Romley@nih.gov.Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation.